CLINICAL EFFICACY OF TEMOZOLOMIDE AND ITS PREDICTORS IN AGGRESSIVE PITUITARY TUMORS AND PITUITARY CARCINOMAS: A SYSTEMATIC REVIEW AND META-ANALYSIS

Clinical Efficacy of Temozolomide and Its Predictors in Aggressive Pituitary Tumors and Pituitary Carcinomas: A Systematic Review and Meta-Analysis

Background: A growing number of evidences suggest that TMZ applications can generate impressive benefits for APT and PC patients.However, the definite role of TMZ for individuals remains unclarified due to the variation between studies.And the predictive factors to alter its efficacy remain debatable.Objective: To evaluate the long-term effectivene

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Sequential Portal Vein Embolization and Percutaneous Radiofrequency Ablation for Future Liver Remnant Growth: A Minimally Invasive Alternative to ALPPS Stage-1 in Treatment of Hepatocellular Carcinoma

Background: To evaluate the feasibility and efficacy of sequential portal vein embolization (PVE) and radiofrequency ablation (RFA) (PVE+RFA) as a minimally invasive variant for associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) stage-1 in treatment of Hip Chairs cirrhosis-related hepatocellular carcinoma (HCC).Meth

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Identification of protective pneumococcal T(H)17 antigens from the soluble fraction of a killed whole cell vaccine.

Mucosal or parenteral immunization with a killed unencapsulated pneumococcal whole cell antigen (WCA) with an adjuvant protects mice from colonization by a T(H)17 CD4+ cell-mediated mechanism.Using preparative SDS gels, we separated the soluble proteins that compose the WCA in order to identify fractions that were immunogenic and protective.We scre

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